发明名称 USE OF CARBOXYLIC ACID AMIDES
摘要 Use of compounds of the formula <IMAGE> I wherein R1, R2, R3, R4 and R5, independently are hydrogen, alkyl, or C3-7-cycloalkyl or two adjacent residues R1 to R5 taken together with adjacent carbons of the phenyl ring form a 5- to 7-membered ring optionally substituted by one or more lower alkyl groups; X is -NR7-CO- or -CO-NR7-; R6 is hydroxy, lower-alkoxy or -NR8R9; and R7, R8 and R9, independently, are hydrogen or lower-alkyl, and where R6 is hydroxy, their pharmaceutically usable salts, for the treatment of inflammatory and rheumatic diseases.
申请公布号 AU8088487(A) 申请公布日期 1988.05.12
申请号 AU19870080884 申请日期 1987.11.05
申请人 HOFFMANN-LA ROCHE, F. & CO. A.G., 发明人 MICHAEL KLAUS
分类号 A61K31/195;A61K31/165;A61K31/19;A61K31/235;A61P29/00;C07C67/00;C07C231/00;C07C233/65;C07C233/81;C07C237/42 主分类号 A61K31/195
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