NITROXIDE COMPOUNDS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION INTENDED FOR THE PROPHYLAXIS AND TREATMENT OF ISCHEMIC CELL DAMAGE

摘要

The use of an organochemical compound comprising the structural unit where R is selected from the group consisting of (i) unpaired electron, (ii) a cation such as a physiologically acceptable metal ion, (iii) hydrogen and (iv) a protective group which is known per se for hydroxyl groups and which can readily be cleaved off, and the alpha and alpha' carbon atoms are substituted in a manner such that if R = unpaired electron the compound is a stable nitroxide (stable nitroxyl radical), for the preparation of a pharmaceutical composition intended for the prophylaxis and treatment of ischemic cell damage. The use comprises a method of preventing and treating ischemic cell damage in nammals.