PROCESS FOR PRODUCING A MATERIAL FOR AFFINITY CHROMATOGRAPHY

摘要

The material is prepared by binding a sulphated polysaccharide to a carrier material with amino groups. …For this, a sulphated polysaccharide is treated with an oxidising agent which oxidises glycols to aldehydes with cleavage of the carbon chain, and this modified sulphated polysaccharide is reacted with a carrier with amino groups. …The affinity material can be used for adsorption and, where appropriate, subsequent desorption of proteins which bind to sulphated polysaccharides from solutions of these proteins, e.g. antithrombin III from blood plasma.