发明名称 |
Synthesis of hydroxysulfone and related compounds |
摘要 |
This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma. |
申请公布号 |
AU6780396(A) |
申请公布日期 |
1997.03.19 |
申请号 |
AU19960067803 |
申请日期 |
1996.08.26 |
申请人 |
MERCK & CO., INC.;ZENECA LIMITED |
发明人 |
DAVID J. MATHRE;PAUL SOHAR;DAVID MOODY;ANDREW J. BLACKER |
分类号 |
C07D495/04 |
主分类号 |
C07D495/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|