| 发明名称 |
AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS |
| 摘要 |
The present invention relates to a novel thrombin inhibitor which is effective even when orally administered. More specifically, the present invention relates to an aromatic amidine derivative represented by formula (I) and the salts thereof, which show potent selective inhibitory activity for thrombin in which (a), R, R1, R2, R3, A, W, Y and n are defined as described in the specification.
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| 申请公布号 |
CA2256438(A1) |
申请公布日期 |
1997.12.04 |
| 申请号 |
CA19972256438 |
申请日期 |
1997.05.31 |
| 申请人 |
C & C RESEARCH LABORATORIES |
发明人 |
HONG, WOO SANG;KIM, JONG MIN;KOO, BON AM;RYU, EUN JUNG;NAM, WOONG HYUN;MIN, JAE KI |
| 分类号 |
C07D401/06;A61K31/00;A61K31/40;A61K31/4025;A61K31/403;A61K31/404;A61K31/415;A61K31/4164;A61K31/4184;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/4465;A61K31/4523;A61K31/454;A61K31/47;A61K31/472;A61K31/4725;A61P7/00;A61P7/02;C07D207/08;C07D401/14;C07D403/06;C07D403/14;C07D405/06;C07D405/14;C07D409/06;C07D409/14;(IPC1-7):C07D403/06;C07D205/04;C07D413/06;C07D417/06;C07D207/09;C07D207/10;C07D211/34;A61K31/41 |
主分类号 |
C07D401/06 |
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