Rapidly disintegrating tablet and process for the manufacture thereof

摘要

A tablet having an enhanced strength as well as a high disintegrating rate in the oral cavity is prepared by mixing a spray-dried particulate containing an active ingredient, a sublimable substance suitable for oral administration, a poly(ethylene glycol), and a pharmaceutically acceptable additive; tableting the mixture; and drying the resulting tablet to sublime the sublimable substance until the tablet becomes porous.