发明名称 Methods and compositions related to cyclic peptide synthesis
摘要 Disclosed are compositions and methods for cyclization of polymers such as peptides.
申请公布号 US9365622(B2) 申请公布日期 2016.06.14
申请号 US200712281373 申请日期 2007.03.01
申请人 University of Utah Research Foundation 发明人 Schmidt Eric W.;Hathaway Brian;Nelson James T.;Donia Mohamed S.
分类号 C07K14/00;C07K5/12;C07K7/02;C07K7/06;C07K7/64 主分类号 C07K14/00
代理机构 Ballard Spahr LLP 代理人 Ballard Spahr LLP ;Marty Scott
主权项 1. A peptide comprising an amino acid segment comprising: the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE, an amino acid sequence at least about 90% identical to the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE, or the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE having one or more conservative amino acid substitutions; wherein N1 and/or N2 comprises an amino acid sequence, wherein N1 or N2 do not comprise one or more of the amino acids A, C, I, F, L, P, S, T, or V.
地址 Salt Lake City UT US