发明名称 | Methods and compositions related to cyclic peptide synthesis | ||
摘要 | Disclosed are compositions and methods for cyclization of polymers such as peptides. | ||
申请公布号 | US9365622(B2) | 申请公布日期 | 2016.06.14 |
申请号 | US200712281373 | 申请日期 | 2007.03.01 |
申请人 | University of Utah Research Foundation | 发明人 | Schmidt Eric W.;Hathaway Brian;Nelson James T.;Donia Mohamed S. |
分类号 | C07K14/00;C07K5/12;C07K7/02;C07K7/06;C07K7/64 | 主分类号 | C07K14/00 |
代理机构 | Ballard Spahr LLP | 代理人 | Ballard Spahr LLP ;Marty Scott |
主权项 | 1. A peptide comprising an amino acid segment comprising: the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE, an amino acid sequence at least about 90% identical to the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE, or the amino acid sequence of GLEAS(N1)AYDGVEPS(N2)AYDGE having one or more conservative amino acid substitutions; wherein N1 and/or N2 comprises an amino acid sequence, wherein N1 or N2 do not comprise one or more of the amino acids A, C, I, F, L, P, S, T, or V. | ||
地址 | Salt Lake City UT US |