发明名称 |
PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES |
摘要 |
The invention concerns compounds of formula (I): in which in particular: R1 represents an alkyl or arylalkyl radical; X-Y represents CH-CH2, N-CH2, C=CH or NCH2CH2; n represents a whole number between 2 and 10; Z represents O or NH; Ar represents an aromatic radical such as a phenyl or a naphthyl; R2 represents a linear or branched alkyl radical comprising 1 to 6 carbon atoms. The invention is useful as medicine, in particular as selective antagonists of human 5-HT1A, 5-HT1D and 5-HT1B receptors.
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申请公布号 |
WO9842692(A1) |
申请公布日期 |
1998.10.01 |
申请号 |
WO1998FR00542 |
申请日期 |
1998.03.18 |
申请人 |
PIERRE FABRE MEDICAMENT;HALAZY, SERGE;LAMOTHE, MARIE;JORAND-LEBRUN, CATHERINE |
发明人 |
HALAZY, SERGE;LAMOTHE, MARIE;JORAND-LEBRUN, CATHERINE |
分类号 |
C07D295/092;C07D295/13;C07D401/12;(IPC1-7):C07D295/08;C07D295/12;A61K31/495 |
主分类号 |
C07D295/092 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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