| 发明名称 |
Heterosubstituted pyridine derivatives as LTiGTpde 4LT/iGT inhibitors |
| 摘要 |
The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE 4).or a pharmaceutically acceptable salt or hydrate thereof.The invention also encompasses pharmaceutical compositions and methods for treatment. |
| 申请公布号 |
AU4282900(A) |
申请公布日期 |
2000.11.21 |
| 申请号 |
AU20000042829 |
申请日期 |
2000.05.03 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
BERNARD COTE;RICHARD FRIESEN;RICHARD FRENETTE;MARIO GIRARD;YVES GIRARD;CEDRICKX GODBOUT;DANIEL GUAY;PIERRE HAMEL;MARC BLOUIN;YVES DUCHARME;SYLVIE PRESCOTT |
| 分类号 |
A61K31/444;A61K31/4725;A61P1/04;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/00;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P25/02;A61P25/24;A61P25/28;A61P27/02;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D213/74;C07D213/76;C07D213/79;C07D213/89;C07D401/14;C07D405/14;C07D409/14;C07D417/14 |
主分类号 |
A61K31/444 |
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