The present invention is directed to compounds and methods for the treatment of metastatic disease. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase that is overexpressed in metastatic tumor cells. The compounds used in accordance with this invention may be provided in a pharmaceutical composition for treatment of metastatic disease.
申请公布号
PT1242060(E)
申请公布日期
2006.08.31
申请号
PT20000955687T
申请日期
2000.08.17
申请人
GLAXO GROUP LIMITED;PURDUE RESEARCH FOUNDATION;UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人
KINCH, MICHAEL, SCOTT;KILPATRICK, KATHERINE E;ZANTEK, NICOLE, D.;HEIN, PATRICK, W.
