| 发明名称 | Thermosensitive injectable hydrogel for drug delivery | ||
| 摘要 | The invention develops a developed a thermosensitive injectable hydrogel based on HA and a copolymer of polyethylene oxide (PEO) and polypropylene oxide (PPO), which has a gel formation temperature from 30° C. to 37° C. The thermosensitive injectable hydrogel of the invention provides a potential drug delivery system that can increase therapeutic efficacy of the drug. | ||
| 申请公布号 | US9364545(B2) | 申请公布日期 | 2016.06.14 |
| 申请号 | US201414309266 | 申请日期 | 2014.06.19 |
| 申请人 | TAIPEI MEDICAL UNIVERSITY | 发明人 | Jhan Hua-Jing;Ho Hsiu-O;Sheu Ming-Thau;Shen Shing Chuan;Ho Yuan Soon;Liu Jun-Jen |
| 分类号 | A61K31/337;A61K31/704;A61K47/34;A61K47/36;A61K9/06 | 主分类号 | A61K31/337 |
| 代理机构 | WPAT, P.C., Intellectual Property Attorneys | 代理人 | WPAT, P.C., Intellectual Property Attorneys ;King Anthony |
| 主权项 | 1. A thermosensitive injectable hydrogel, which has a gel formation temperature from 30° C. to 37° C. and comprises an HA polymer and a copolymer of polyethylene oxide (PEO) and polypropylene oxide (PPO), wherein the amounts of HA and the polymer are about 0.01% (w/v) to about 0.2% (w/v) and about 15% (w/v) to about 18% (w/v), respectively; wherein HA has a mean molecular weight of about 1,500,000 Da to about 2,500,000 Da. | ||
| 地址 | Taipei TW | ||