| 摘要 |
Ethers of azadibenzocyclo heptene-5-ol of general formula (I) and their salts and quaternary ammonium cpds. X= -CH2-CH2- or -CH=CH- R1 and R2=same or different H, hal (pref. Cl or Br) or C1-8 alkyl R3=a basic N group contng. less than 16C atoms R3 may be -A-B- where A=C1-8 alkylene and B=(C1-8 alkyl)amino, di(C1-8 alkyl)amino, piperidino, pyrrolidino, morpholino, thiamorpholino or R3 may be the group where R4=H, C1-8 alkyl m=0, 1 or 2 n=1 or 2 or satd. bicyclic heterocyclic e.g. tropan-3-yl. Antihistamine, also sedative, spasmolytic and anti-depressive properties. |
