摘要 |
5-Bromo-6-fluoro steroids are produced by the bromine-fluorine addition to the double bond of a DELTA 5 -unsaturated steroid using an N-bromoacylamide or N-bromoimide and aqueous hydrogen fluoride. A novel steroid produced by the process is 6 beta -fluoro-5 alpha -bromo-3 beta ,17 beta -dihydroxy-androstane.
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