摘要 |
Compositions adapted for administration to a portion of the surface of the body of a warm-blooded animal comprise, as active ingredient, at least one compound of formula I <IMAGE> wherein X1 represents a hydrogen, fluorine, chlorine or bromine atom; X2 represents a fluorine, chlorine or bromine atom, X3 represents a chlorine, bromine or iodine atom and R represents a benzyl radical (optionally substituted by one or more substituents from C1-4 alkyl radicals, C2-6 alkenyl radicals, C2-6 alkenyloxy radicals, C4-8 alkadienyl radicals, methylenedioxy radicals, benzyl radicals and halogen atoms); a group of formula: <IMAGE> a group of formula: <IMAGE> or a group of formula: <IMAGE> or a group of formula: <IMAGE> (in which the symbol S/I indicates an aromatic ring or dihydro or tetrahydro analogue thereof); said active ingredient being in association with a vehicle capable of permitting passage of the active ingredient through the skin barrier of the animal, R1-R9 being defined as in Claim 1. |