Method for preparing cis-bicyclo[3.3.0]octylidene derivative

摘要

A method for preparing a cis-bicyclo[3.3.0]octylidene derivative represented by the formula: <IMAGE> wherein R1 is a hydrogen atom or an alkyl group; R2 is a hydrogen atom or a protective group for hydroxyl group; and Y is <IMAGE> where R3 is a hydrogen atom or a protective group for hydroxyl group; R4 is a hydrogen atom or a straight, branched or cyclic alkyl group, alkenyl group or alkynyl group; and X is a group represented by CH=CH or C 3BOND C, comprises carrying out the catalytic hydrogenation reaction of a (1-alkenyl)-cis-bicyclo[3.3.0]octene derivative represented by the formula: <IMAGE> wherein R1, R2 and Y have the same meanings as defined above, in the presence of a metal carbonyl compound or its complex represented by the formula: Mw(CO)x(H)y(R)z wherein M is a metal element of the group VIB; R is a pi ligand or a phosphine ligand; w is 1 or 2; x is an integer of 3 to 6; y is 0 or 1; and z is 0 or an integer of 1 to 3.