发明名称 Polyethoxylated vitamin E and process for its preparation
摘要 The present invention relates to a polyethoxylated vitamin E corresponding to the following formula (I): <IMAGE> in which R is -(CH2CH2-O)nH, n is an integer from 2 to 100 A is <IMAGE> or <IMAGE> , B is -CH3 in the 5-, 7- or 8-position and m is an integer from 1 to 3. The compound of the invention, which can be prepared by reacting a vitamin E or an ester of the latter with ethylene oxide, using a basic catalyst under pressure and under anhydrous conditions, has an anti-oxidising nature and a stability to oxidation similar to those of vitamin E acetate and very favourable moisture-retaining and surface activity properties not found in vitamin E and vitamin E acetate. Moreover, the compound is very safe to use in living organisms. The present invention also relates to a process for preparing the compound (I) and to some of its uses.
申请公布号 FR2674525(A1) 申请公布日期 1992.10.02
申请号 FR19920003745 申请日期 1992.03.27
申请人 PACIFIC CHEMICAL CO LTD 发明人 KIM YOUNG DAE;HA BYNNG JO
分类号 A61K8/00;A61K8/67;A61K31/352;A61K31/355;A61P43/00;A61Q5/00;A61Q19/00;B01F17/00;C07D311/72;C08G65/26;C08G65/28;C08G65/34 主分类号 A61K8/00
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