Vial adaptors and vials for regulating pressure

摘要

An adaptor for coupling with a vial, the adaptor comprising: 5 a housing member defining a distal extractor aperture configured to permit withdrawal of fluid from the vial when the adaptor is coupled to the vial; a connector configured to couple to the housing member with the vial; a piercing member connected to the housing member and configured to be inserted in the vial, the piercing member defining a distal regulatory aperture; 10 a bag having an interior filled with pre-pressurized, sterilized gas; a removable cover configured to maintain a relatively stable pressure within the bag while the removable cover is placed between the interior of the bag and ambient air; and a regulator channel configured to permit at least some of the sterilized gas 15 to move from the bag through the distal regulator aperture to the vial.