4- (METHYLAMINOPHENOXY) PYRDIN-3-YL-BENZAMIDE DERIVATIVES FOR TREATING CANCER

摘要

THE PRESENT INVENTION PROVIDES A NOVEL COMPOUND HAVING AN EXCELLENT ANTITUMOR EFFECT, STABILITY AND METABOLIC STABILITY. THE COMPOUND OF THE PRESENT INVENTION IS REPRESENTED BY THE FOLLOWING GENERAL FORMULA (1) WHEREIN R1 REPRESENTS A HALOGEN ATOM, AN ARYL GROUP, AN ARYLOXY GROUP OR A LOWER ALKYL GROUP OPTIONALLY SUBSTITUTED WITH ONE OR MORE HALOGEN ATOMS; R2 REPRESENTS A HYDROGEN ATOM, A HALOGEN ATOM, A LOWER ALKYL GROUP OR A LOWER ALKOXY GROUP; AND; M REPRESENTS AN INTEGER OF 1 TO 3; PROVIDED THAT WHEN M REPRESENTS 2 OR 3, R1S ARE THE SAME OR DIFFERENT.