| 发明名称 |
CARBOXYMETHYL-GROUP-CONTAINING MODIFIED HYALURONIC ACID AND/OR SALT THEREOF AND/OR PRODUCTION METHOD FOR CARBOXYMETHYL-GROUP-CONTAINING MODIFIED HYALURONIC ACID AND/OR SALT THEREOF |
| 摘要 |
A method of producing a carboxymethyl-group-containing modified hyaluronic acid and/or a salt thereof includes a step of subjecting, in a water-containing solvent having a temperature of 30° C. or less, a dissolved raw material hyaluronic acid and/or a salt thereof to a reaction with a haloacetic acid and/or a salt thereof, the water-containing solvent including water or a liquid mixture of a water-soluble organic solvent and water, a ratio of the water-soluble organic solvent in the liquid mixture being 60 v/v % or less. |
| 申请公布号 |
US2016244534(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201415027841 |
申请日期 |
2014.10.07 |
| 申请人 |
KEWPIE CORPORATION |
发明人 |
Fujikawa Shunichi;Abe Yukina;Asaoka Kazunori;Yoshida Takushi |
| 分类号 |
C08B37/08;A61K47/36;A61Q19/00;A61K9/14;A61Q17/04;A61Q5/02;A61Q5/12;A61K9/48;A61K8/73;A61Q19/10 |
主分类号 |
C08B37/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of producing a carboxymethyl-group-containing modified hyaluronic acid and/or a salt thereof,
the method comprising a step of subjecting, in a water-containing solvent having a temperature of 30° C. or less, a dissolved raw material hyaluronic acid and/or a salt thereof to a reaction with a haloacetic acid and/or a salt thereof, the water-containing solvent comprising water or a liquid mixture of a water-soluble organic solvent and water, a ratio of the water-soluble organic solvent in the liquid mixture being 60 v/v % or less. |
| 地址 |
Tokyo JP |
