摘要 |
The reduction of N-[(N', N' -disubstituted amino)-alkyl]adamantane-1-carboxamides affords the corresponding diamines, which are acylated to yield N-acyl-N-[(N',N'-disubstituted amino)alkyl]-1-adamantylmethylamines. The latter compounds are useful as pharmacological agents, as is evidenced by their anti-inflammatory, anti-microbial and anti-spasmodic properties.
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