| 摘要 |
1377350 Basic ethers CHEMIE LINZ AG 6 Sept 1973 [11 Sept 1972] 42063/73 Heading C2C Compounds of the general formula (R = C 1-4 alkyl; R 1 = H, C 1-4 alkyl, allyl, PhCH 2 ; R 2 =C 2-6 alkenyl, ar(C 2-4 alkenyl) optionally C 1-4 alkoxy substituted, C 2-6 haloalkenyl, C 2-3 alkynyl, C 3-6 cycloalkyl, cycloalkylidenemethyl containing up to seven carbon atoms; R 3 =H, Me) and their salts are prepared by reacting a compound of the formula (X=NHR 4 , N=CHR 5 ; R 4 =C 1-4 alkyl, allyl, PhCH 2 , acyl; R 5 = aryl, optionally substituted) with R 2 CH 2 Hal (Hal=halogen) and removing any CHR 5 or acyl group present in the product, optionally followed by introduction of an R 1 substituent and/or salt formation. The starting materials are prepared by standard methods. The above compounds are analgesics, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. |
