Novel phenethylamine derivatives and processes for preparing same

摘要

A compound of the formula: <IMAGE> (I) wherein R is methyl or 2-methylthioethyl, is prepared by either (A) condensing a compound of the formula: <IMAGE> (II) wherein R is the same as above, or a reactive derivative thereof with 3,4-diethoxycarboxyphenethylamine, or (B) condensing the compound (II) or a reactive derivative thereof with dopamine, followed by reacting the resultant product with an ethoxycarbonyl halide. The compound (I) shows potent renal blood flow-increasing activity and is useful for the treatment of renal hypertension, congestive heart failure and other diseases due to renal blood flow disturbances.