发明名称 PROCESS FOR PURIFICATION OF PHARMACOLLOGICALLY ACTIVE PROTEINS THGROUGH CATIONIC EXCHANGE CHROMATOGRAPHY
摘要 The subject matter of the invention is a procedure of purification of pharmacollogically active proteins, through the use of cationic exchange chromatography on the solid carrier done on the primary pH, i.e. higher, in relation to pH appropriate to the electric point, pI protein that are purified, pH whereon the mentioned proteins although residual yet get absorbed. The solvents of buffer with pH and ionic strength adjusted from time to time to the type of pharmacologically active proteins that are purified are used for preparation of such results. The procedure mainly relates to purification of interferon and albumins.
申请公布号 YU50502(A) 申请公布日期 2005.09.19
申请号 YU2002P000505 申请日期 2002.06.26
申请人 ALFA WASSERMANN S.P.A. 发明人 SCAPOL, LUCIA;OT, VISCOMI GIUSEPPE CLAUDIO
分类号 C12N15/09;A61K38/00;A61K38/21;A61P31/12;A61P43/00;C07K1/18;C07K14/555;C07K14/56;C07K14/565;C07K14/76;C07K14/765 主分类号 C12N15/09
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