发明名称 |
PROCESS FOR PURIFICATION OF PHARMACOLLOGICALLY ACTIVE PROTEINS THGROUGH CATIONIC EXCHANGE CHROMATOGRAPHY |
摘要 |
The subject matter of the invention is a procedure of purification of pharmacollogically active proteins, through the use of cationic exchange chromatography on the solid carrier done on the primary pH, i.e. higher, in relation to pH appropriate to the electric point, pI protein that are purified, pH whereon the mentioned proteins although residual yet get absorbed. The solvents of buffer with pH and ionic strength adjusted from time to time to the type of pharmacologically active proteins that are purified are used for preparation of such results. The procedure mainly relates to purification of interferon and albumins. |
申请公布号 |
YU50502(A) |
申请公布日期 |
2005.09.19 |
申请号 |
YU2002P000505 |
申请日期 |
2002.06.26 |
申请人 |
ALFA WASSERMANN S.P.A. |
发明人 |
SCAPOL, LUCIA;OT, VISCOMI GIUSEPPE CLAUDIO |
分类号 |
C12N15/09;A61K38/00;A61K38/21;A61P31/12;A61P43/00;C07K1/18;C07K14/555;C07K14/56;C07K14/565;C07K14/76;C07K14/765 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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