发明名称 |
Pro-micelle pharmaceutical compositions |
摘要 |
The present invention provides pro-micelle compositions comprising a pharmaceutically active agent encapsulated with a membrane of esterified C<SUB>12</SUB>-C<SUB>18 </SUB>fatty acids. In the mammalian intestine, exposure to C<SUB>12</SUB>-C<SUB>18 </SUB>fatty acids results in conversion of the pro-micelle to a stable micelle that effectively delivers the pharmaceutically active agent to the systemic circulation. The present invention further provides methods of making and using such compositions.
|
申请公布号 |
US6951655(B2) |
申请公布日期 |
2005.10.04 |
申请号 |
US20010974942 |
申请日期 |
2001.10.11 |
申请人 |
IMI BIOMED, INC. |
发明人 |
CHO YOUNG W.;LEE KWANG-HO |
分类号 |
A61K9/107;A61K9/00;A61K9/127;A61K9/14;A61K9/48;A61K9/50;A61K9/64;A61K38/28;A61K47/14;A61K47/24;A61K47/42;(IPC1-7):A61K9/127;A61K37/18 |
主分类号 |
A61K9/107 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|