发明名称 |
CLONING VEHICLES FOR POLYPEPTIDE EXPRESSION IN MICROBIAL HOSTS |
摘要 |
<p>Methods and compositions are provided for expression of polypeptides in transformed bacterial hosts. A novel class of plasmid cloning vehicles includes a DNA sequence coding for the desired polypeptide linked in reading phase with one or more functional fragments derived from an outer membrane protein gene of a gram-negative bacterium. The methods utilize such plasmids to introduce genetic capability into micro-organisms for the production of proteins, such as medically or commercially useful hormones, enzymes, immunogenic proteins, or intermediates therefor.</p> |
申请公布号 |
CA1207684(A) |
申请公布日期 |
1986.07.15 |
申请号 |
CA19820393567 |
申请日期 |
1982.01.05 |
申请人 |
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (THE) |
发明人 |
NAKAMURA, KENZO;INOUYE, MASAYORI |
分类号 |
C07H21/04;C12N1/20;C12N15/00;C12P21/02;(IPC1-7):C12N15/00 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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