发明名称 |
MINACTIVIN |
摘要 |
Minactivin, a protein inactivator of urokinase-type plasminogen activator, has been shown to be a natural inactivator of this plasminogen activator which is associated with invasive tumours, and is therefore indicated as a crucial element in the body's normal defense against tumour invasion and metastasis. It may be produced by the cultivation of miniactivin-producing cells in vitro, and recovery of the cell culture supernatant. By controlling the culture conditions, the protein miniactivin may be produced in a partially purified form which may be used for diagnosis and treatment of tumours. |
申请公布号 |
WO8601212(A1) |
申请公布日期 |
1986.02.27 |
申请号 |
WO1985AU00191 |
申请日期 |
1985.08.13 |
申请人 |
BIOTECHNOLOGY AUSTRALIA PTY. LTD.;THE AUSTRALIAN NATIONAL UNIVERSITY |
发明人 |
STEPHENS, ROSS, WENTWORTH;GOLDER, JEFFREY, PHILIP;GOSS, NEIL, HOWARD;ANTALIS, TONI, MARIE |
分类号 |
G01N33/68;A61K35/12;A61K35/14;A61K35/24;A61K35/28;A61K35/38;A61K38/00;A61K38/46;A61K38/55;A61K39/00;A61K39/395;A61P35/00;C07K1/20;C07K1/22;C07K14/00;C07K14/435;C07K14/47;C07K14/81;C07K16/00;C07K19/00;C12N5/00;C12P21/00;C12Q1/56;C12R1/91;G01N33/574;(IPC1-7):C07K15/06 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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