Compositions and method of controlling transdermal penetration of topical and systemic agents

摘要

Compositions and methods useful for improved and controlled transdermal and transmembrane drug delivery of topical and systemic agents. The compositions and methods comprise a pharmacologically active drug together with a non-toxic pharmaceutically acceptable ion exchange resin, and a salt in a gel-forming vehicle and topically administering to human or animal skin or other membranes the resulting compositions. If desired, a penetration enhancer may also be employed in the compositions of this invention.