发明名称 |
PEPTIDES STIMULATING CYTOTOXIC T CELLS IMMUNE TO HIV RT |
摘要 |
The subject invention relates to a peptide having the amino acid sequence Glu-Ile-Cys-Thr-Glu-Met-Glu-Lys-Glu-Gly-Lys-Ile-Ser-Lys-Ile-Gly-Pro or portions thereof. This peptide is derived from, or based upon, a region of a relatively conserved epitope of HIV-1 reverse transcriptase. The peptide may be utilized in the treatment of patients having human immunodeficiency virus or in the prevention of infection of those individuals who have been exposed to the disease, yet have not become sero-positive. The preparation containing the peptide may be administered either subcutaneously, intramuscularly or intravenously. |
申请公布号 |
AU7556691(A) |
申请公布日期 |
1991.10.10 |
申请号 |
AU19910075566 |
申请日期 |
1991.03.08 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, |
发明人 |
JAY A. BERZOFSKY;RONALD N GERMAIN;CHARLES D PENDLETON;BERNARD MOSS;GENE MARTIN SCHEARER;ANN HOSMALIN;MARIO CLERICI |
分类号 |
A61K38/00;A61K39/00;A61K39/21;A61P31/12;A61P37/04;C07K7/08;C07K14/00;C07K14/16;C07K14/52;C07K14/54;C07K14/55;C12N5/10;C12N15/09;C12P21/02;C12Q1/70;G01N33/53;G01N33/569 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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