| 摘要 |
<p>This invention provides methods for identifying tumors which may be susceptible to treatment by chemotherapy or radiation by detecting the presence of nucleic acid encoding Id in the tumor or by detecting the presence of an Id protein in the tumor and a method for in situ identification of tumors which may be susceptible to treatment by chemotherapy or radiation. This invention also provides antisense oligonucleotides, a pharmaceutical composition comprising an amount of the oligonucleotide, methods of inducing terminal differentiation in a tumor cell, and methods of treating a tumor in a subject.</p> |
