| 发明名称 |
A NOVEL SMAD3 SPLICE VARIANT AS A TARGET IN CHRONIC RENAL FAILURE, ATHEROSCLEROSIS AND FIBROSIS |
| 摘要 |
sMAD3d polypeptides and polynucleotides and methods for producing such polypepti des by recombinant techniques are disclosed. Also disclosed are methods for utilizing sMAD3d polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal failure, atherosclerosis, and fibrosis, among others, and diagnostic assays for such cond itions.
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| 申请公布号 |
CA2238670(A1) |
申请公布日期 |
1999.02.01 |
| 申请号 |
CA19982238670 |
申请日期 |
1998.07.24 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
LAPING, NICHOLAS;ZHU, YUAN |
| 分类号 |
C12N15/09;A61K31/70;A61K31/7105;A61K31/711;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61P9/10;A61P11/00;A61P13/02;A61P13/12;A61P15/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/00;C12N15/12;C12P21/02;C12Q1/02;C12Q1/68;C12R1/91;G01N33/15;G01N33/50;(IPC1-7):C12N15/12;A61K38/17;G01N33/53 |
主分类号 |
C12N15/09 |
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