发明名称 |
PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2 ' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER. |
摘要 |
Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase. |
申请公布号 |
MX339822(B) |
申请公布日期 |
2016.06.13 |
申请号 |
MX20130009815 |
申请日期 |
2012.02.29 |
申请人 |
NUCANA BIOMED LIMITED |
发明人 |
Christopher MCGUIGAN;Jan BALZARINI;Blanka GONCZY;Paola MURZIANI;MAGDALENA SLUSARCZYK |
分类号 |
C07F9/6558;A61K31/675;A61P35/00 |
主分类号 |
C07F9/6558 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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