发明名称 METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF CRYSTALLINE MICROPARTICLE SURFACES FOR ACTIVE AGENTS
摘要 Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.
申请公布号 CA2621806(C) 申请公布日期 2016.08.02
申请号 CA20062621806 申请日期 2006.09.14
申请人 MANNKIND CORPORATION 发明人 OBERG, KEITH A.
分类号 A61K47/22;A61K9/14;A61K9/16 主分类号 A61K47/22
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