| 摘要 |
1,213,637. 9-Fluorocortisol derivatives. E. R. SQUIBB & SONS Inc. 30 Nov., 1967 [21 Dec., 1966], No. 54513/67. Heading C2U. [Also in Division A5] Novel compounds of formula [wherein R is C 1-12 hydrocarbon carboxylic acyl, W is C 1-6 alkylsulphonyloxy and X is halo) are prepared from the corresponding 21-ols by reaction with alkanesulphonyl halides, and are convertible by the action of an alkali metal iodide and an acid into the corresponding compounds wherein W is H. 9α-Fluorocortisol 17-acetate is prepared from 9α-fluorocortisol via 9α-fluorocortisol 17,21- (methyl orthoacetate). |
