发明名称 |
Methods and compositions for the identification of metastatic human tumors |
摘要 |
Disclosed are monoclonal antibodies which react with human tumor cells, particularly metastatic human tumor cells, but not with normal human tissues tested. The monoclonal antibodies are prepared against a 580 kilodalton glycoprotein antigen, designated gp580, which is isolated from either rat or human tumor cells. Methods for isolating the glycoprotein antigen are disclosed as well. Moreover, techniques are disclosed for utilizing these antibodies both in the detection and in the prevention of human tumor lesions.
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申请公布号 |
US5030559(A) |
申请公布日期 |
1991.07.09 |
申请号 |
US19860846938 |
申请日期 |
1986.04.01 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
NICOLSON, GARTH L.;NORTH, SUSAN M.;STECK, PETER A. |
分类号 |
C07K14/195;A61K38/00;A61K39/00;C07K14/00;C07K14/005;C07K14/705;C07K16/00;C07K16/30;C07K19/00;C12N5/00;C12N5/06;C12N15/00;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/574;G01N33/577 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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