Derivatives of 2-spirocyclopropyl 4-acylcephem sulfones of the formula (I) <IMAGE> (I) are provided which are useful as potent elastase inhibitors and hence are useful in the prevention, control and treatment of inflammatory conditions, especially arthritis and emphysema.
申请公布号
US5258377(A)
申请公布日期
1993.11.02
申请号
US19910681680
申请日期
1991.04.08
申请人
TAIHO PHARMACEUTICAL CO., LTD.
发明人
MAITI, SAMARENDRA N.;REDDY, NARENDER A. V.;CZAJKOWSKI, DAVID;SPEVAK, PAUL;FIAKPUI, CHARLES;MICETICH, RONALD G.