发明名称 |
QUINOLONES AS SERINE PROTEASE INHIBITORS |
摘要 |
This invention discloses quinolinones which display inhibitory effects on serine proteases such as factor Xa, thrombin and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.
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申请公布号 |
WO9950263(A1) |
申请公布日期 |
1999.10.07 |
申请号 |
WO1998US26709 |
申请日期 |
1998.12.15 |
申请人 |
WARNER-LAMBERT COMPANY;DUDLEY, DANETTE, ANDREA;EDMUNDS, JEREMY, JOHN |
发明人 |
DUDLEY, DANETTE, ANDREA;EDMUNDS, JEREMY, JOHN |
分类号 |
A61K31/4704;A61K31/4709;A61P7/02;A61P9/00;A61P43/00;C07D215/22;C07D215/227;C07D401/06;C07D401/14;C07D403/06;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/14;C07D417/12;C07D417/14;(IPC1-7):C07D401/06;C07D407/14;A61K31/44;A61K31/47 |
主分类号 |
A61K31/4704 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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