SAMMENSÆTNING OG FORMULERING OMFATTENDE REKOMBINANT HUMANT IDURONAT-2-SULFATASE OG FREMGANGSMÅDE TIL FREMSTILLING DERAF

摘要

Disclosed is a composition comprising recombinant iduronate-2-sulfatase (IDS). The glycosylation pattern and formylglycine content of the IDS composition are different from those of Elaprase and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of Hunter syndrome.