发明名称 Improved blood storage unit and method of storing blood
摘要 Blood storage units comprising containers with aqueous preservative solutions therein are improved by incorporating dihydroxyacetone (DHA) together with L-ascorbate (vitamin C) in the preservative solutions. The invention also relates to a method of storing human blood wherein viable red cells are stored in contact with both DHA and L-ascorbate. The preservative solution of the blood storage unit may also contain an anticoagulant such as citrate, a sugar energy source such as dextrose, and an ATP maintaining agent such as adenine. Where the blood storage unit is to be heat sterilized, as preferred, a blood bag providing a separate compartment for part of the preservative agents prevents deterioration of the preservative agents, the DHA and sugar energy source being heat sterilized separately for later admixture with the ascorbate, citrate anticoagulant and adenine. Separate pH control can also thereby be provided for the heat sterilization.
申请公布号 US3874384(A) 申请公布日期 1975.04.01
申请号 US19730345961 申请日期 1973.03.29
申请人 AMERICAN HOSPITAL SUPPLY CORPORATION 发明人 DEINDOERFER, FRED H.;BRAKE, JON M.
分类号 A61J1/00;A61J1/05;A61J1/12;A61J1/14;(IPC1-7):A61J1/00;A61K17/00;C12K9/00 主分类号 A61J1/00
代理机构 代理人
主权项
地址