发明名称 |
BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES AND METHOD FOR PREPARING SAME |
摘要 |
New biologically active drug polymer derivatives, namely peptides or protein der ivatives, are useful medicaments and are represented by the generic formula: RO-(CH2-CH2O)n-(CO)-NH-X-(CO)-NH-Z, wherein R represents a lower alkyl group, n is an integer comprised between 25 and 250, X when combined with adjacent NH and CO groups represents an amino acid or a dipeptide or tripeptide residue, and Z when combined with the adjacent NH g roup represents a biologically active peptide or protein or NH or NH2 containing drug residue.
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申请公布号 |
CA2038935(C) |
申请公布日期 |
1998.12.08 |
申请号 |
CA19902038935 |
申请日期 |
1990.07.26 |
申请人 |
DEBIOPHARM S.A. |
发明人 |
SARTORE, LUCIANA;ORSOLINI, PIERO;DEGHENGHI, ROMANO;VERONESE, FRANCESCO |
分类号 |
A61K31/13;A61K31/43;A61K31/70;A61K31/77;A61K38/00;A61K38/04;A61K38/21;A61K38/22;A61K38/23;A61K38/27;A61K38/28;A61K38/44;A61K38/46;A61K47/48;(IPC1-7):A61K47/48 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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