发明名称 BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES AND METHOD FOR PREPARING SAME
摘要 New biologically active drug polymer derivatives, namely peptides or protein der ivatives, are useful medicaments and are represented by the generic formula: RO-(CH2-CH2O)n-(CO)-NH-X-(CO)-NH-Z, wherein R represents a lower alkyl group, n is an integer comprised between 25 and 250, X when combined with adjacent NH and CO groups represents an amino acid or a dipeptide or tripeptide residue, and Z when combined with the adjacent NH g roup represents a biologically active peptide or protein or NH or NH2 containing drug residue.
申请公布号 CA2038935(C) 申请公布日期 1998.12.08
申请号 CA19902038935 申请日期 1990.07.26
申请人 DEBIOPHARM S.A. 发明人 SARTORE, LUCIANA;ORSOLINI, PIERO;DEGHENGHI, ROMANO;VERONESE, FRANCESCO
分类号 A61K31/13;A61K31/43;A61K31/70;A61K31/77;A61K38/00;A61K38/04;A61K38/21;A61K38/22;A61K38/23;A61K38/27;A61K38/28;A61K38/44;A61K38/46;A61K47/48;(IPC1-7):A61K47/48 主分类号 A61K31/13
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