| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivative of benzimidazole of the formula (I) <EMI ID=0.308 HE=27 WI=33 TI=CHI> where R - a residue of the formula (a) <EMI ID=0.309 HE=21 WI=27 TI=CHI> where each A, B and D means CH or one or two of A, B and D means N and other are CH; R - monocyclic heteroaryl taken from pyrimidine, imidazole, pyrrole, thiazole, oxadiazole, pyrazole, pyridine, furan possibly substituted with lower alkyl, amino-group, pyridyl, oxadiazolyl; one of R and R - hydrogen atom and other - furanyl or isoxazolyl, or its pharmaceutically acceptable salt or oxide or pharmaceutical composition on its base that provides modulation of GAOA-receptor complex of living organism central nervous system. EFFECT: valuable pharmacological properties of compound. 8 cl, 2 tbl, 45 ex
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