| 摘要 |
The present invention relates to oligonucleotides which hybridize specifically to the cytosine DNA methyltransferase gene of Neisseria gonorrhoeae and distinguish the cytosine DNA methyltransferase gene of N. gonorrhoeae from highly homologous sequences which have been discovered in some strains of other species of the genus Neisseria. The oligonucleotides are useful as primers for the polymerase chain reaction (PCR) amplification of a nucleic acid sequence from the cytosine DNA methyltransferase gene of N. gonorrhoeae and in N. gonorrhoeae amplification/detection assays. The invention has applications in the detection of Neisseria gonorrhoeae, the field of medical diagnostics generally, and the field of molecular biology |
