VEGF Related gene and protein

摘要

The invention provides isolated nucleic acid compounds, proteins and peptides, said proteins and peptides being related to the VEGF family of angiogenic ligands. Also provided are vectors and transformed heterologous host cells for expressing the proteins. Also provided are methods for identifying compounds that bind and/or modulate the activity of said proteins, methods for treating cancer or inhibiting tumor growth by administration of an antagonist of VEGF-R, and methods for stimulating angiogenesis in a patient in need thereof by administration of a therapeutically effective amount of VEGF-R.