| 摘要 |
PURPOSE:To provide a dermatic agent for external use by combining a vitamin E having age-preventive effect against sagging of skin and loss of skin luster, etc., as well as chap-preventive and ameliorating effect with a p- methoxycinnamic acid ester compound, thereby increasing the above effects without causing side effects. CONSTITUTION:A dermatic agent for externals use having high age-preventive effect as well as chap-preventive and ameliorating effect can be produced by compounding (A) one or more compounds selected from vitamin E and its derivative (e.g. acetate, nicotinate, succinate, linolenate, etc.) and (B) one or more kinds of p-methoxycinnamic acid ester compound of formula I-V (R<1> is 5-17C alkyl derived from saturated side-chain fatty acid; R<2> is 1-2C alkyl; R<3> is OCH3 substituted to ortho or para position). The amount of the component A in the whole dermatic agent is 0.005-2wt%, preferably 0.05-0.5wt%, and that of the component B is >=1/100pts.wt., preferably >=1pt.wt. per 1pt.wt. of the component A. |
