Inhibitors of cruzipain and other cysteine proteases

摘要

A compound according to general formula (I) or general formula (II) useful as an inhibitor of the protease cruzipain, a gene product of the Trypanosoma cruzi parasite, as well as other cysteine proteases. Also disclosed are pharmaceutical compositions comprising such compounds, useful for the therapeutic treatment of Trypanosoma cruzi infection, for example, in Chagas' disease.