Method for treatment and prevention of mastitis

摘要

Disclosed is a method of treating or preventing mastitis caused by Escherichia coli in a non-human mammal, comprising administration to the mammal during dry period of an oxazolidinone selected from the group (S)-N-[[3-[3-fluoro-4-(morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide and N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-1,3-oxazolidnin-5-yl]methylacetamide. Also disclosed is a method of treating or preventing mastitis Escherichia coli in a non-human mammal, comprising administration of one of the above oxazolidinones in combination with lactoferrin in an amount sufficient to enhance the therapeutic effect of the oxazolidinone.