| 摘要 |
Provided are a superior dipeptidyl peptidase-IV inhibitor and the like. Specifically provided are a dipeptidyl peptidase-IV inhibitor, a hypoglycemic agent and a vascular endothelial dysfunction inhibitor, each comprising, as an active ingredient, one or more peptides selected from among peptides comprising one of the amino acid sequences represented by (a)-(d): (a) Ser-Pro-Ala-Gln (SEQ ID NO: 1), (b) Gly-Pro-Val-Arg (SEQ ID NO: 2), (c) His-Pro-His-Pro-His (SEQ ID NO: 3), and (d) Ala-Pro-Lys (SEQ ID NO: 4). Also provided are new peptides comprising any one of the amino acid sequences represented by (a)-(c): (a) Ser-Pro-Ala-Gln (SEQ ID NO: 1), (b) Gly-Pro-Val-Arg (SEQ ID NO: 2), and (c) His-Pro-His-Pro-His (SEQ ID NO: 3). |
