发明名称 |
derivados de imidazol como inibidores de enzima pde10a |
摘要 |
This invention is directed to compounds (I) which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable earner. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating, a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. |
申请公布号 |
BR112013012378(A2) |
申请公布日期 |
2016.08.30 |
申请号 |
BR20131112378 |
申请日期 |
2011.11.18 |
申请人 |
H. LUNDBECK A/S |
发明人 |
JACOB NIELSEN;JAN KEHLER;JOHN PAUL KILBURN;MAURO MARIGO;MORTEN LANGGARD |
分类号 |
C07D519/00;A61K31/519;A61P25/00;A61P25/18;A61P25/24 |
主分类号 |
C07D519/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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