| 发明名称 |
Method for Eliciting an Immune Response to Human Telomerase Reverse Transcriptase |
| 摘要 |
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers. |
| 申请公布号 |
US2016263203(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
US201514984959 |
申请日期 |
2015.12.30 |
| 申请人 |
GERON CORPORATION ;THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
CECH THOMAS R.;LINGNER JOACHIM;NAKAMURA TORU M.;CHAPMAN KAREN B.;MORIN GREGG B.;HARLEY CALVIN B.;ANDREWS WILLIAM H. |
| 分类号 |
A61K39/00;C07K14/435;C12N9/12;A61K39/39 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated polypeptide comprising 10 or more consecutive amino acids of SEQ. ID NO:2, which can elicit an adaptive immune response against human telomerase reverse transcriptase (hTRT; SEQ. ID NO:2). |
| 地址 |
MENLO PARK CA US |
