发明名称 Substd indoles as anti inflammatory agents
摘要 <p>Cpds. are of formula: (where R is H, halogen, haloalkyl, CN, COOH, alkoxy, OH, NH2, N(Alk)2, Alkyl, NO2 NHAlk, NHAcyl, SH, SAlk, SOAlk, SO2Alk2 Alk(NH)-alk, AlkOalk, COOAlk, aralkoxy or acyl, n =1-4, R1 and R2 are H or alkyl, Z is a heterocyclic or homocyclic opt. substd. ring system contng. less than 3 rings, X is CO or COCH:CH, and Y is a polar group contng. an acid proton of pKa 2-6 esp a phosphonic acid, ester or amide a sulphonic acid or ester, a sulphinic acid or sulphonamido group) as well as their salts, esters, anhydrides and amides.</p>
申请公布号 BE745065(A1) 申请公布日期 1970.07.01
申请号 BED745065 申请日期 1970.01.28
申请人 MERCK + CY. INC., 126 EAST LINCOLN AVENUE, RAHWAY, NEW JERSEY,E.U.A. 发明人
分类号 C07D209/10;(IPC1-7):61K/;07D/ 主分类号 C07D209/10
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