Verfahren zur Herstellung von Thionosalicylsäureaniliden

摘要

(A) Thionosalicylic acid anilides where R = H or an acid radical R1 = H, lower alkyl, lower alkoxy R2 = H, halogen, lower alkyl, lower alkoxy. R3, R4, and R5 are the same or diff. and = H, OH, lower alkyl, lower alkoxy, halogen, nitro, haloalkyl, alkylmercapto or acyloxy. X and Y are the same or diff. and = H, halogen or nitro with the proviso that X and Y cannot both be hydrogen at the same time and in the case where X is hydrogen, Y can only be Cl or Br when each of R3, R4 and R5 is different. Compounds (I) and their salts have parasiticidal activity in sheep and cattle particularly against liver flukes. They are also active antibacterial, antifungal and antiprotozoal agents. Compounds (IV) have similar uses.